HOMOCYSTEINE BLOOD TESTS

HOMOCYSTEINE, VITAMINS AND HEART DISEASE

Q. What is homocysteine? .

A. While not as potent a risk factor for heart disease as cholesterol, homocysteine like high cholesterol, at high blood concentrations can damage artery walls and contribute to the blocking of  blood vessels. Homocysteine concentrations now widely accepted as normal are associated with an increased likelihood of coronary artery disease and that this risk increases with rising homocysteine concentrations.?

Homocysteine is an amino acid (one of the chemical compounds that forms proteins). Everyone produces it, mainly from eating animal products. Normally the substance is converted into other non-damaging amino acids. But in some people,  this conversion is sluggish and results in the accumulation of homocysteine in the blood.

Studies indicate that this problem is strongly influenced by diet -- specifically, low blood levels of  vitamins B-6, B-12 and folic acid in particular. These vitamins convert homocysteine into other harmless amino acids. So its being suggested by some health professionals and supplement manufacturers that consuming more of  these vitamins may, at least in part, decrease homocysteine concentrations and cardiovascular disease risk.

Too much folic acid can mask vitamin B12 deficiency and extremely high doses of B6 can cause  nerve damage. The AHA recommends that we obtain adequate intakes of these vitamins by eating a variety of foods, rather than supplements. Good sources of folic acid are citrus fruits, tomatoes, vegetables and grain products. The richest sources of B6 are chicken, fish, liver, pork, kidney and eggs as well as unmilled rice, soybeans, oats, and whole-wheat products. The richest sources of B12 are animal products, peanuts and walnuts.

Dr. Martin is now routinely performing Homocysteine levels on his patients. If you are interested in having this blood test, please contact the office.